Solutions from the Earth - Doctors warn against consuming Grapefruit juice if you take certain types of medication, such as statins, which are metabolized by the CYP3A4 enzyme. Grapefruit juice inhibits this
![Lack of CYP3A4 Inhibition by Grapefruit Juice and Ketoconazole upon Clozapine Administration in Vivo | Semantic Scholar Lack of CYP3A4 Inhibition by Grapefruit Juice and Ketoconazole upon Clozapine Administration in Vivo | Semantic Scholar](https://d3i71xaburhd42.cloudfront.net/bdbe648c8841c3c1c62c95bacfe7f70d8c5c1290/9-Table2-1.png)
Lack of CYP3A4 Inhibition by Grapefruit Juice and Ketoconazole upon Clozapine Administration in Vivo | Semantic Scholar
![TWO MAJOR GRAPEFRUIT JUICE COMPONENTS DIFFER IN INTESTINAL CYP3A4 INHIBITION KINETIC AND BINDING PROPERTIES | Drug Metabolism & Disposition TWO MAJOR GRAPEFRUIT JUICE COMPONENTS DIFFER IN INTESTINAL CYP3A4 INHIBITION KINETIC AND BINDING PROPERTIES | Drug Metabolism & Disposition](https://dmd.aspetjournals.org/content/dmd/32/10/1146/F1.large.jpg)
TWO MAJOR GRAPEFRUIT JUICE COMPONENTS DIFFER IN INTESTINAL CYP3A4 INHIBITION KINETIC AND BINDING PROPERTIES | Drug Metabolism & Disposition
البورد العراقي للصيدلة السريرية - Drug Interactions with Grapefruit &grapefruit Juice: ♧Grapefruit juice decreases the activity(enzyme inhibiter) of the cytochrome P450 3A4 (CYP3A4) enzymes that are responsible for breaking down many drugs
![Assessment of a Candidate Marker Constituent Predictive of a Dietary Substance–Drug Interaction: Case Study with Grapefruit Juice and CYP3A4 Drug Substrates | Journal of Pharmacology and Experimental Therapeutics Assessment of a Candidate Marker Constituent Predictive of a Dietary Substance–Drug Interaction: Case Study with Grapefruit Juice and CYP3A4 Drug Substrates | Journal of Pharmacology and Experimental Therapeutics](https://jpet.aspetjournals.org/content/jpet/351/3/576/F1.large.jpg)
Assessment of a Candidate Marker Constituent Predictive of a Dietary Substance–Drug Interaction: Case Study with Grapefruit Juice and CYP3A4 Drug Substrates | Journal of Pharmacology and Experimental Therapeutics
![Food-drug interactions precipitated by fruit juices other than grapefruit juice: An update review - ScienceDirect Food-drug interactions precipitated by fruit juices other than grapefruit juice: An update review - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S1021949818300371-fx1.jpg)
Food-drug interactions precipitated by fruit juices other than grapefruit juice: An update review - ScienceDirect
![Inactivation of Cytochrome P450 3A4 by Bergamottin, a Component of Grapefruit Juice | Chemical Research in Toxicology Inactivation of Cytochrome P450 3A4 by Bergamottin, a Component of Grapefruit Juice | Chemical Research in Toxicology](https://pubs.acs.org/cms/10.1021/tx970192k/asset/images/large/tx970192kf00004.jpeg)